Oxford Haemodynamic Adaptation to Reduce Pulsatility trial (OxHARP)

A double-cross-over placebo controlled randomised clinical trial on the effects of two phosphodiesterase inhibitors (Sildenafil and Cilostasol) on cerebrovascular reactivity and the pulsatility of cerebral blood flow; funded by Wellcome Trust grant (206589/Z/17/Z).

I acquire clinical, physiological and neuroimaging data and develope the analysis pipelines for the neuroimaging data.
ClinicalTrials.gov: NCT03855332; Neuroimaging protocol;